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See Full PDF See Full PDFJournal of the American Academy of Dermatology
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Acne is a common inflammatory skin disease which affects the pilosebaceous units of the skin. It can have severe psychological effects and can leave the patient with severe skin scarring. There are four well-recognized pathological factors responsible for acne which is also the target for acne therapy. In this review, different treatment options are discussed, including topical (i.e., retinoids, and antibiotics) and systemic (i.e., retinoids, antibiotics, and hormonal) treatments. Since the general public has been showing an increasing interest in more natural and generally safer treatment options, the use of complementary and alternative medicines (CAM) for treating acne was also discussed. The use of physical therapies such as comedone extraction, cryoslush therapy, cryotherapy, electrocauterization, intralesional corticosteroids and optical treatments are also mentioned. Acne has been extensively researched with regards to the disease mechanism as well as treatment options. However, due to the increasing resistance of Propionibacterium acnes towards the available antibiotics, there is a need for new treatment methods. Additionally, the lack of necessary evidence on the efficacy of CAM therapies makes it necessary for researchers to investigate these treatment options further.
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People perceive acne as a minority disorder (not a major health concern), but it has a significant impact and burden on the victims. Although conventional drugs are available for its treatment, which are applied directly to the affected skin, such as azelaic acid, benzoyl peroxide, and salicylic acid etc. or formulations that are applied to the skin and taken by mouth such as Antibiotics and retinoids as well as birth control pills. This paper discusses the contemporary issues related to conventional treatment of acne with a view of exploring the way forward. Relevant literatures of stakeholders report and studies conducted globally and locally were searched and reviewed. Economic, environmental, emotional, social and spiritual issues are the major contemporary issues related to acne conventional treatment. The article recommend the use of scientific evidence based herbals for acne as it is a promising strategy and the real pharmacy today with no side effects.
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Australian family physician
Acne is one of the commonest dermatological problems, experienced by approximately 80% of Western adolescents. If left untreated it can be the source of significant physical sequelae and psychological problems. Prevalence studies show that acne is not just a problem of youth but for some, it persists into middle age. To review both the causes of acne and current acne management issues in relation to problems and options for improving outcomes. The earlier acne is treated the more likely scarring will be minimised, so a proactive approach is important. The development of oral isotretinoin has offered those with severe, nodulocystic acne the chance of not only disease containment but suppression. However, it is still the only available treatment that targets all four pathological processes involved in acne. The development of antibiotic resistance is becoming a global problem and causing a need to revise our approach to acne.
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Journal of the American Academy of Dermatology
Scientific advances are continually improving the knowledge of acne and contributing to the refinement of treatment options; it is important for clinicians to regularly update their practice patterns to reflect current standards. The Global Alliance to Improve Outcomes in Acne is an international group of dermatologists with an interest in acne research and education that has been meeting regularly since 2001. As a group, we have continuously evaluated the literature on acne. This supplement focuses on providing relevant clinical guidance to health care practitioners managing patients with acne, with an emphasis on areas where the evidence base may be sparse or need interpretation for daily practice.
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